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EC Number Crystallization (Commentary) Reference
Display the reaction diagram Show all sequences 2.7.1.1812.2 A resolution structure reveals a bacterial methyltransferase domain joined to a eukaryotic kinase domain. The kinase domain is again fused to an extended C-terminal coiled-coil domain reminiscent of eukaryotic Myotonic Dystrophy Protein Kinase family kinases. Structures of co-complexes with two known eukaryotic protein kinase inhibitors which are potent inhibitors in vitro, but do not show any in vivo activity 728331
Display the reaction diagram Show all sequences 2.7.1.181crystallization and modeling by molecular-replacement to obtain high-resolution diffraction, and development of methods to control the hydration status 726580
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