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EC Number Crystallization (Commentary) Reference
Show all pathways known for 2.6.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.36- 637017, 637018, 675405
Show all pathways known for 2.6.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.36docking experiments based on crystal structure PDB code 2CJH in order to identify enzyme inhibitors 688801
Show all pathways known for 2.6.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.36hanging drop vapour diffusion method in 0.1 M trisodium citrate dihydrate solution containing 0.2 M ammonium acetate and 25% PEG 4000 in the pH range 5.4-6.0 671149
Show all pathways known for 2.6.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.36molecular docking of inhibitors 4-methoxy-2-(pyridin-4-yl)-2,3-dihydro-1,3-thiazole-5-carboxylic acid, 2-phenyl-4-(prop-2-yn-1-yloxy)-2,3-dihydro-1,3-thiazole-5-carboxylic acid, 4-ethoxy-2-phenyl-2,3-dihydro-1,3-thiazole-5-carboxamide. Ligands are found in the vicinity of the Arg422, Gln274, Lys300, Arg170, Phe167, Glu243 amino acid residues. Compounds can make favourable interactions with important amino acid residues such as Arg170, Arg440, and Lys300 739738
Show all pathways known for 2.6.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.36strcutures of mutants T330S, E243A, N328A, to 2.7-1.95 A resolution 737607
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