EC Number |
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2.5.1.1 | enzyme forms a heterotetramer of two catalytic large plus two regulatory small subunits. No activity is detected for individually expressed large or small subunits |
2.5.1.1 | microbatch-under-oil method, crystal structures of apoenzyme, ligand-bound enzyme, and inhibitor-bound structures |
2.5.1.1 | molecular dynamics simulations for wild-type and mutants Q107E, L110W, Q107F, Q107F/L110A, L110A |
2.5.1.1 | vapour diffusion in a sitting drop at 22°C. Crystalized in the presence of farnesyl diphosphate, and its X-ray structure is determined at 1.9 A resolution |