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EC Number Crystallization (Commentary)
Show all pathways known for 1.1.1.203Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.203crystal structures of an apo-form, a ternary form in complex with NADH and product, and an inactive Y136A mutant in complex with NAD+. Enzyme is a homohexamer. The monomer contains a Rossmann fold, essential for nucleotide binding. The ternary complex structure reveals a product, D-galactaro-1,5-lactone, which is bound above the nicotinamide ring. This product rearranges in solution to D-galactaro-1,4-lactone
Show all pathways known for 1.1.1.203Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.203enzyme structure, PDB ID 3AY3
Show all pathways known for 1.1.1.203Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.203sitting drop vapor diffusion method, using 0.1 M MES pH6.5 and 30% (w/v) 2-methyl-2-4-pentanediol
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