 2.7.8.B13 | structures of PgsA1 in absence of substrates (2.9 A), in complex with Mn2+ and citrate (1.9 A), and with the CDP-DAG substrate (1.8 A). The nucleotide moiety of the substrate is bound into a cleft formed by transmembrane helices 1-3, lined by G72, A75, and G85 and exposed to solvent. The long acyl chains of the substrate are disordered |