EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
2.7.1.78 | -999 |
- |
more |
- |
642024 |
2.7.1.78 | -999 |
- |
more |
effect of A12B4C3 binding on the W331F mutant, 95% inhibition |
704680 |
2.7.1.78 | -999 |
- |
more |
effect of A12B4C3 binding on the W402F mutant, 6% inhibition |
704680 |
2.7.1.78 | -999 |
- |
more |
effect of A12B4C3 binding on the WFX402 mutant, 90% inhibition |
704680 |
2.7.1.78 | -999 |
- |
more |
effect of A12B4C3 binding on the wild-type PNKP, 100% inhibition |
704680 |
2.7.1.78 | 0.2 |
- |
diphosphate |
pH 5.5, 37°C |
642010 |
2.7.1.78 | 0.2 |
- |
sulfate |
competitive versus ATP, pH 5.5, 37°C |
642015 |
2.7.1.78 | 0.5 |
- |
sulfate |
pH 5.5, 37°C |
642010 |
2.7.1.78 | 3 |
- |
beta,gamma-imidoadenylyl 5'-tetraphosphate |
versus ATP, pH 8.0, 35°C, independent of pH-value |
642014 |
2.7.1.78 | 3.8 |
- |
ADP |
pH-independent in the range pH 6.0-8.5, 30°C |
642024 |