EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
2.1.2.2 | -999 |
- |
more |
4-carbamoyl-2-[4-[4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(2,2,2-trifluoroacetyl)butyl]benzoylamino]butyric acid and 4-carbamoyl-4-[4-[4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(2,2,2-trifluoroacetyl)butyl]benzoylamino]butyric acid show Ki-values above 0.1 mM |
672527 |
2.1.2.2 | 0.000005 |
0.00005 |
N-[(5-[2-[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl]-4-methylthiophen-2-yl)carbonyl]glutamic acid |
pH and temperature not specified in the publication |
735672 |
2.1.2.2 | 0.000005 |
0.00005 |
N-[(5-[2-[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl]thiophen-2-yl)carbonyl]glutamic acid |
pH and temperature not specified in the publication |
735672 |
2.1.2.2 | 0.000005 |
0.00005 |
N-[(5-[2-[(6S)-2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimido[5,4-b][1,4]thiazin-6-yl]ethyl]thiophen-2-yl)carbonyl]glutamic acid |
pH and temperature not specified in the publication |
735672 |
2.1.2.2 | 0.000007 |
- |
N-[4-[4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophene-2-carbonyl]-L-glutamic acid |
at pH 7.5 and 37°C |
756039 |
2.1.2.2 | 0.000009 |
- |
N-[4-[4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophene-2-carbonyl]-L-glutamic acid |
at pH 7.5 and 37°C |
756039 |
2.1.2.2 | 0.000014 |
- |
10-formyl-DDACTHF |
- |
688291 |
2.1.2.2 | 0.000014 |
- |
10-formyl-DDACTHF |
26°C, pH 7.5 |
672526 |
2.1.2.2 | 0.000015 |
- |
10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
- |
658000 |
2.1.2.2 | 0.000015 |
- |
10-CF3CO-DDACTHF |
- |
688291 |