EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
1.3.5.2 | 0.00001 |
- |
dichloro-allyllawsone |
- |
391242 |
1.3.5.2 | 0.0000232 |
- |
brequinar sodium |
full-length native enzyme |
390922 |
1.3.5.2 | 0.0000265 |
- |
brequinar sodium |
recombinant enzyme |
390922 |
1.3.5.2 | 0.00005 |
- |
2-cyano-3-(9-ethyl-9H-carbazol-3-ylamino)acrylic acid ethyl ester |
- |
675315 |
1.3.5.2 | 0.000061 |
- |
Lapachol |
- |
391242 |
1.3.5.2 | 0.000067 |
- |
dichloro-allyllawsone |
- |
391242 |
1.3.5.2 | 0.000174 |
- |
decylubiquinone |
wild type enzyme, at pH 8.0 and 25°C |
725920 |
1.3.5.2 | 0.0002 |
0.0009 |
2-hydroxyethylidene-cyanoacetic acid 4-trifluoromethyl anilide |
competitive to dihydroorotate |
391233 |
1.3.5.2 | 0.0002 |
0.0009 |
2-hydroxyethylidene-cyanoacetic acid 4-trifluoromethyl anilide |
competitive to ubiquinone, non-competitive to dihydroorotate, parent compound leflunomide has no inhibitory effect at concentrations up to 0.001 mM |
391241 |
1.3.5.2 | 0.000333 |
- |
decylubiquinone |
mutant enzyme N302S, at pH 8.0 and 25°C |
725920 |