EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
1.7.3.3 | -999 |
- |
more |
1-methylurate, 3-methylurate, 7-methylurate do not inhibit significantly |
394180 |
1.7.3.3 | 0.00035 |
- |
oxonate |
mutant enzyme V144A/Y319R, at pH 7.4 and 25°C |
765718 |
1.7.3.3 | 0.00042 |
- |
oxonate |
mutant enzyme Y319R, at pH 7.4 and 25°C |
765718 |
1.7.3.3 | 0.00045 |
- |
oxonate |
mutant enzyme V144A, at pH 7.4 and 25°C |
765718 |
1.7.3.3 | 0.00052 |
- |
oxonate |
wild type enzyme, at pH 7.4 and 25°C |
765718 |
1.7.3.3 | 0.0021 |
- |
8-nitroxanthine |
competitive inhibitor versus urate at pH 8.0 |
671971 |
1.7.3.3 | 0.0042 |
- |
oxonate |
mutant enzyme Y319R, at pH 9.2 and 25°C |
765718 |
1.7.3.3 | 0.0049 |
- |
oxonate |
mutant enzyme V144A, at pH 9.2 and 25°C |
765718 |
1.7.3.3 | 0.0049 |
- |
oxonate |
mutant enzyme V144A/Y319R, at pH 9.2 and 25°C |
765718 |
1.7.3.3 | 0.0056 |
- |
oxonate |
wild type enzyme, at pH 9.2 and 25°C |
765718 |