EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
|---|
   3.4.21.27 | 0.00000081 |
- |
protease nexin-2 |
in 50 mM Tris, 150 mM NaCl, 5 mM CaCl2, 0.1% (w/v) bovine serum albumin, pH 7.5, at 37°C |
717742 |
| 3.4.21.27 | 0.00000081 |
- |
protease nexin-2 mutant M17A |
in 50 mM Tris, 150 mM NaCl, 5 mM CaCl2, 0.1% (w/v) bovine serum albumin, pH 7.5, at 37°C |
717742 |
| 3.4.21.27 | 0.00000093 |
- |
protease nexin-2 mutant S19A |
in 50 mM Tris, 150 mM NaCl, 5 mM CaCl2, 0.1% (w/v) bovine serum albumin, pH 7.5, at 37°C |
717742 |
| 3.4.21.27 | 0.000001 |
- |
protease nexin 2 |
mutant enzyme E98A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.00000103 |
- |
N-[(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl]-4-(aminomethyl)-2-fluorobenzamide |
at 25°C, pH not specified in the publication |
731462 |
| 3.4.21.27 | 0.0000011 |
- |
protease nexin 2 |
mutant enzyme E98V, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.00000116 |
- |
N-[(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl]-4-(aminomethyl)benzamide |
at 25°C, pH not specified in the publication |
731462 |
| 3.4.21.27 | 0.0000012 |
- |
(2E)-N-[(1S)-1-[4-(3-amino-1H-indazol-6-yl)-5-chloro-1H-imidazol-2-yl]-2-phenylethyl]-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enamide |
at 25°C, pH not specified in the publication |
731462 |
| 3.4.21.27 | 0.0000013 |
- |
protease nexin 2 |
mutant enzyme R3704A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.0000013 |
- |
protease nexin 2 |
mutant enzyme Y143A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
