EC Number   |
Cofactor |
Reference |
|---|
   5.4.99.4 | adenosylcobalamin |
- |
651581 |
| 5.4.99.4 | cob(II)alamin |
- |
651581 |
| 5.4.99.4 | cobamide |
acts as a carrier for the hydrogen atom that is abstracted from alpha-methyleneglutarate. The enzyme contains 4 cobalamin molecules per tetramer. The cobalamins consist of adenosylcobalamin and cobalamin(II). Enzyme containing adenosylcobalamin is the active form of the enzyme but the enzyme containing cobalamin(II) is stable to oxygen and is an inactive form of the enzyme |
3526 |
| 5.4.99.4 | cobamide |
dependent on |
3527 |
| 5.4.99.4 | cobamide |
e.g. alpha-(5,6-dimethylbenzimidazolyl)cobamide coenzyme, Km: 0.000073 mM, alpha-(benzimidazolyl)-cobamide coenzyme, Km: 0.0003 mM, or alpha-(adenyl)-cobamide coenzyme, Km: 0.00125 mM. The most effective coenzyme is alpha(5,6-dimethylbenzimidazolyl)-cobamide coenzyme |
3522 |
| 5.4.99.4 | cobamide |
required |
3453, 3522 |
| 5.4.99.4 | cobamide |
the enzyme contains adenosylcobalamin and varying amounts of oxygen-stable cob(II)alamin. The content of total cobalamin is 2-4 mol/ml enzyme, the content of cob(II)alamin is 6-11% of the total cobalamin. The oxygen-stable cob(II)alamin is not involved in catalysis |
3529 |
| 5.4.99.4 | vitamin B12 |
- |
661159 |
| 5.4.99.4 | vitamin B12 |
contains 2.1 mol of this coenzyme per homotetramer |
3530 |
| 5.4.99.4 | vitamin B12 |
dependent on |
2986, 3453, 3524, 3528, 3531 |
