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EC Number Cofactor Commentary Reference
Show all pathways known for 4.2.1.9Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.9Fe-S center - 732214
Show all pathways known for 4.2.1.9Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.9[2Fe-2S]-center DHAD can accommodate [Fe2S2] and [Fe4S4] clusters. Only the [Fe2S2] cluster-bound form is catalytically active. The [Fe2S2] cluster is coordinated by at least one non-cysteinyl ligand, which can be replaced by the thiol group(s) of dithiothreitol. [Fe2S2] cluster-containing NFU2 protein is likely the physiological cluster donor for in vivo maturation of DHAD 748233
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