EC Number   |
Cofactor |
Reference |
|---|
    4.2.1.22 | heme |
- |
649869, 649888, 649914, 650105, 650154, 652551, 652695, 681230, 697850, 698157, 701064, 701929, 704974, 713958, 714071, 715172, 729799 |
| 4.2.1.22 | heme |
2 mol per mol of tetrameric enzyme |
5601, 5602 |
| 4.2.1.22 | heme |
b-type heme |
650096 |
| 4.2.1.22 | heme |
carbon monoxide or nitric oxide can bind to the cofactor, resulting in enzyme inhibition |
680641 |
| 4.2.1.22 | heme |
CO binding displaces Cys52 from the heme |
704177 |
| 4.2.1.22 | heme |
cystathionine beta-synthase binds one mole of heme per subunit |
677837 |
| 4.2.1.22 | heme |
dependent |
652694 |
| 4.2.1.22 | heme |
enzyme possesses a noncatalytic heme cofactor with cysteine and histidine as ligands. Nitrite is reduced by Fe(II)-CBS to form Fe(II)NO radical-CBS. Reoxidation of Fe(II)NO radical-CBS by O2 shows complex kinetic behavior and leads to peroxynitrite (ONOO-) formation |
748214 |
| 4.2.1.22 | heme |
ferrous CBS can form a complex with isonitriles |
649570 |
| 4.2.1.22 | heme |
ferruous CBS can form a complex with isonitriles |
649570 |
