EC Number |
Cofactor |
Reference |
---|
2.7.11.22 | ATP |
- |
489976, 490796, 490797, 490800, 660948, 662124, 662152, 662686, 662688, 662855, 662926, 663933, 664005, 664030, 664160, 664179, 664332, 664536, 664955, 665053, 665056, 665488, 665497, 665645, 665840, 665862, 665968, 665977, 665980, 665982, 666109, 666117, 666120, 666124, 666184, 666185, 666186, 666340, 666347, 666401, 666466, 666467, 666468, 666575, 666588, 666624, 666635, 666718, 666728, 666744, 678926, 690991, 691554, 695013, 707369, 707637, 707843, 707917, 707985, 707997, 708041, 708631, 708648, 708842, 709335, 709585, 709637, 721248, 721817, 721962, 721986, 722194, 722706, 722744, 723022, 723073, 723176, 723178, 723423, 723513, 723656, 723745 |
2.7.11.22 | ATP |
ATP binding pocket structure, the pocket is a cleft located at the interface between two domains, involvd residues, overview |
664689 |
2.7.11.22 | ATP |
binding at the active site between the C- and N-terminal enzyme domains |
666862 |
2.7.11.22 | ATP |
dependent on |
490935 |
2.7.11.22 | ATP |
mutant Cdk1-as1 has an enlarged ATP binding site |
666440 |
2.7.11.22 | ATP |
the binding site is a deep pocket lined by hydrophobic residues, enzyme affinity of cdk2 for ATP is not influenced by phosphorylation of the activation loop |
490931 |
2.7.11.22 | cyclin |
- |
680759, 681873, 690991, 691272, 691554, 691679, 691982, 691988, 693022, 693721, 693746, 693747, 693758, 693762, 693903, 694081, 694150, 694187, 694491, 695204, 707369, 707637, 707843, 707997, 708041, 708631, 708648, 708842, 709335, 709510, 709585 |
2.7.11.22 | cyclin |
active CDK-cyclin oscillates during the cell cycle |
664332 |
2.7.11.22 | cyclin |
dependent on |
693779 |
2.7.11.22 | cyclin |
dependent on as regulatory subunit |
663933 |