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Results 1 - 8 of 8
EC Number Cofactor Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ - 288698, 288700, 288701, 288702, 704662
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ absolute requirement 288698
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ cannot be replaced by NADP+, NADPH, NADH 288697
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ NAD+ seems to function as hydride acceptor in the first part of the reaction and subsequently as hydride donor in the second part 288699
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ required in catalytic amounts with a Km-value of 0.0025 mM 288697
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NAD+ unique usage of NAD(H) as a prosthetic group. the cofactor is coordinated through hydrogen bonding via residues Ser21, Ile22, Ser230 (phosphate), Asp45, Val66 (adenosine), Ser92,Thr114, Ala161, Asn162, and Pro163 (nicotineamide riboside). The phosphate-binding motif (18GFGSIG23) is located in the loop connecting beta-strand 2 and alpha-helix A of the Rossmann fold. The adenosine part of NAD+ is bound via loop regions located between beta-strand 4, 5, 6 and alpha-helix C, D, E. Nicotineamide-riboside-binding residues are found in loop regions between beta-strand 7 and 8 and alpha-helix F and O 739672
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NADH unique usage of NAD(H) as a prosthetic group. the cofactor is coordinated through hydrogen bonding via residues Ser21, Ile22, Ser230 (phosphate), Asp45, Val66 (adenosine), Ser92,Thr114, Ala161, Asn162, and Pro163 (nicotineamide riboside). The phosphate-binding motif (18GFGSIG23) is located in the loop connecting beta-strand 2 and alpha-helix A of the Rossmann fold. The adenosine part of NAD+ is bound via loop regions located between beta-strand 4, 5, 6 and alpha-helix C, D, E. Nicotineamide-riboside-binding residues are found in loop regions between beta-strand 7 and 8 and alpha-helix F and O 739672
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.44NADP+ 68% of the activity with NAD+ 288702
Results 1 - 8 of 8