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Results 1 - 10 of 29 > >>
EC Number Cofactor Commentary Reference
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1more as opposed to the kinetically stabilized carbanion/enamine intermediate in transketolase when reconstituted with the native cofactor, 2-(1,2-dihydroxyethyl)-4'-monomethylaminothiamin diphosphate is rapidly released from the active centers during turnover and accumulates in the medium on a preparative scale 690708
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1NAD+ - 756083
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate - 485992, 485993, 485994, 485995, 485996, 485997, 485998, 485999, 486001, 486004, 486009, 486023, 658646, 672285, 685766, 691270, 691298, 691423, 691433, 691763, 692645, 692925, 693289, 693291, 694066, 735401, 735415, 735416, 735708, 735721, 735856, 735938, 736657, 736993, 756232, 756629, 756713, 756894, 756895, 757041, 757197, 757326, 757895, 758271, 758383, 758509
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate 0.9 mol thiamine diphosphate per mol subunit 486011
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate 1 catalytic site per enzyme molecule 486000
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate 2 catalytic sites per enzyme molecule 486000
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate 2 mol thiamine diphosphate per mol enzyme 486002, 486003, 486007
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate additional thiamine does not enhance activity 486006, 486008, 486011, 486012, 486013
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate an active site cleft is formed between the two monomeric units allowing the cofactors thiamine diphosphate and Mg2+ to bind, such that the N-terminal domain I of chain A binds the diphosphate moiety of thiamine diphosphate, and domain II of chain B interacts with the aminopyrimidine ring. The diphosphate moiety of thiamine diphosphate is anchored in place through a number of hydrogen bonds formed with residues Thr48, His85, Ser176, Asp177, Gly178, Asn207, Ile209 and His283 from one monomer, crystallization data 720609
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1thiamine diphosphate application of a theoretical model of interactions between ligand-binding sites in a dimeric protein for the analysis of thiamine diphosphate binding to yeast transketolase 672632
Results 1 - 10 of 29 > >>