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Results 1 - 10 of 11 > >>
EC Number Cofactor Commentary Reference
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15Ferredoxin ferredoxin may serve as an electron donor 742781
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15flavin iron-sulfur flavoprotein 727782
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15FMN - 742870
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15FMN bioinformatic analysis reveals the presence of one FMN-binding site. The purified protein shows an absorbance peaks at 380 and 460 nm, characteristic of oxidized FMN 727782
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15FMN DmrB contains 2 FMN molecules on the active site at the monomer-monomer interface. The FMN-1 molecule shows ionic interactions with residues Ser110 and Asn116 along with some non-bonded contacts. The FMN-2 molecule shows ionic contacts with Lys123 and Gln120 and pi-pi stacking with the Tyr85 residue. FMN stabilizes and preserves the secondary and quaternary structure of DmrB against thermal insult 764885
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15FMN the enzyme contains one flavin mononucleotide (FMN)-binding site 742781
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15FMN within a homotrimer, each monomer-monomer interface exhibits an active site with two adjacently bound flavin mononucleotide (FMN) ligands, one deeply buried and tightly bound and one more peripheral. Computational docking suggests that the peripheral site binds either the observed FMN (the electron donor for the overall reaction) or the pterin, H2MPT (the electron acceptor for the overall reaction), in configurations ideal for electron transfer to and from the tightly bound FMN. Analysis of the FMN binding structure in the active site, and kinetics, overview 742870
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15more determination of FMN is the cofactor of DmrB, overview 742870
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15more NAD(P)H is incapable of directly reducing the flavin cofactor, but dithionite eliminates the FMN peaks, indicating successful electron transfer to MJ0208. An electron transfer system of NADPH, spinach NADPH-ferredoxin oxidoreductase, and ferredoxin can also reduce the FMN peaks. Dithiothreitol-reduced MJ0208 can transfer electrons to dihydromethanopterin 742781
Show all pathways known for 1.5.99.15Display the reaction diagram Show all sequences 1.5.99.15more NAD(P)H is incapable of directly reducing the flavin cofactor, but dithionite eliminates the FMN peaks, indicating successful electron transfer to MM1854. An electron transfer system of NADPH, spinach NADPH-ferredoxin oxidoreductase, and ferredoxin can also reduce the FMN peaks. Dithiothreitol-reduced MM1854 can transfer electrons to dihydromethanopterin 742781
Results 1 - 10 of 11 > >>