EC Number |
Cofactor |
Reference |
---|
1.2.4.1 | NAD+ |
- |
654462, 654647, 654734, 654741, 655474, 657068, 663808, 684365, 685160, 685585, 686469, 686772, 697756, 698954, 700236, 710839, 712851 |
1.2.4.1 | NAD+ |
required |
726840 |
1.2.4.1 | thiamine diphosphate |
- |
348949, 348951, 348968, 348974, 348981, 654462, 654734, 657000, 657068, 671044, 684365, 685585, 686469, 686772, 687226, 690077, 710839, 712851, 741339, 741340 |
1.2.4.1 | thiamine diphosphate |
dependent |
675426, 685160, 687613, 689791 |
1.2.4.1 | thiamine diphosphate |
dependent on |
725205, 725521, 726840 |
1.2.4.1 | thiamine diphosphate |
dependent on, 2 bound in the V-conformation in clefts between the 2 subunits, completely buried in the structure, binding structure |
654647 |
1.2.4.1 | thiamine diphosphate |
dependent on, binding site |
655474 |
1.2.4.1 | thiamine diphosphate |
dependent on, binding structure and determinants, V conformation, K392 is important |
654741 |
1.2.4.1 | thiamine diphosphate |
kcat/Km value for wild-type 20 per mM and s, for mutant H271A 950 per mM and s |
735664 |
1.2.4.1 | thiamine diphosphate |
KD value 0.00047 mM |
672086 |