EC Number |
Cofactor |
Reference |
---|
1.14.15.4 | adrenodoxin |
- |
724701, 725828, 725981, 726468 |
1.14.15.4 | ascorbate |
plus NADH very low conversion and no aldosterone production, in synergism with NADH, malate and NADP+ increase of aldosterone synthetase activity in zona glomerulosa, not zona fasciculate |
285400 |
1.14.15.4 | Ferredoxin |
- |
673258, 673345 |
1.14.15.4 | Ferredoxin |
[2Fe-2S] ferredoxin |
686714 |
1.14.15.4 | more |
cofactor screening, overview, the enzyme is active with NADPH |
686458 |
1.14.15.4 | NADH |
- |
285400 |
1.14.15.4 | NADH |
less effective than NADPH |
285393 |
1.14.15.4 | NADP+ |
plus malate supports all 4 conversions, increase of aldosterone synthetase activity |
285400 |
1.14.15.4 | NADPH |
- |
285386, 285388, 285389, 285390, 285391, 285392, 285393, 285394, 285395, 285397, 285399, 285400, 285406, 655347, 675052, 675053 |
1.14.15.4 | NADPH |
adrenodoxin and adrenodoxin reductase required in cell line homogenates, in living cells in absence of cofactors |
285407 |