EC Number |
Cofactor |
Reference |
---|
1.1.1.42 | more |
enzyme YlIDP is absolutely dependent on NADP+ and shows no NAD-dependent activity |
739874 |
1.1.1.42 | more |
NAD+ may not replace NADP+ |
668080 |
1.1.1.42 | more |
no activity with NAD+ and NADH |
654843 |
1.1.1.42 | more |
no activity with NADH |
655430 |
1.1.1.42 | more |
SdIDH displays a 19000-32000fold (kcat/Km) preference for NADP+ over NAD+ with Mn2+ and Mg2+, respectively |
723151 |
1.1.1.42 | more |
the enzyme is completely inactive with NAD+ |
723129 |
1.1.1.42 | more |
the enzyme shows a 567 and 193fold preference for NADP+ over NAD+ in the presence of Mg2+ and Mn2+, respectively. The coenzyme specificity of BlIDH can be completely reversed from NADP+ to NAD+ by a factor of 2387 by replacing six residues by rational mutagenesis |
740551 |
1.1.1.42 | NAD+ |
- |
286802, 286808 |
1.1.1.42 | NAD+ |
poor cofactor |
723151 |
1.1.1.42 | NADP+ |
- |
286780, 286781, 286787, 286788, 286791, 286793, 286794, 286795, 286796, 286797, 286799, 286800, 286802, 286803, 286805, 286806, 286807, 286808, 286809, 286810, 286811, 286812, 286813, 654367, 655035, 655142, 655430, 655604, 655663, 656180, 656233, 656431, 656588, 656616, 656740, 657309, 663113, 695502, 696416, 696487, 696823, 698056, 698058, 698059, 699040, 700359, 711092, 711107, 711119, 711330, 712180, 712614, 713100, 713113, 713246, 713508, 721687, 721779, 722338, 722896, 723129, 728770, 739874, 740117, 740122, 740181, 740185, 740551, 740583, 740721, 740946, 741388, 760361, 760369, 760487, 760535, 760832, 761047, 761052, 761403, 761477, 761531, 761559, 761677, 761784, 762026, 762409, 762446, 762498, 762504 |