EC Number   |
Cofactor |
Reference |
|---|
    1.1.1.39 | more |
Arg181 is within hydrogen bonding distance of the 1-carboxylate of malate in the active site of the enzyme and interacts with the carboxamide side chain of the nicotinamide ring of NADH, but not with NAD+ |
685123 |
| 1.1.1.39 | more |
binding site structure of NADH |
656163 |
| 1.1.1.39 | more |
the enzyme uses both NAD+ and NADP+ |
711524 |
| 1.1.1.39 | NAD+ |
- |
654623, 654720, 656983, 657321, 657362, 669132, 685123, 685622, 685678, 687568, 689604, 710948, 711147, 712417, 712942, 713212, 713373, 721353, 721778, 722082, 738272, 741010, 741121, 741191, 761183, 761186, 761744, 762109 |
| 1.1.1.39 | NAD+ |
binding site structure |
654651 |
| 1.1.1.39 | NAD+ |
binding structure, overview |
685215 |
| 1.1.1.39 | NAD+ |
cofactor |
286700, 286701, 286702, 286703, 286704, 286705, 286706, 286707, 286708, 286709, 286710, 286711, 286712, 286713, 286714, 286715, 286716, 286717, 286718, 286719, 286720 |
| 1.1.1.39 | NAD+ |
conformational change upon binding |
656163 |
| 1.1.1.39 | NAD+ |
dependent on |
721357, 722082 |
| 1.1.1.39 | NAD+ |
His362 is involved in NAD+-specific catalysis of NAD-ME, and residue 314 may interact with the bisphosphate of the NAD+ moiety, structure analysis, overview |
723540 |
