EC Number   |
Cofactor |
Reference |
|---|
    1.1.1.205 | 3-acetylpyridine adenine dinucleotide |
- |
724327 |
| 1.1.1.205 | 3-acetylpyridine adenine dinucleotide |
the NAD+ analog 3-acetylpyridine adenine dinucleotide (APAD+) is a substrate for MtIMPDH and the dependence of velocity on increasing concentrations of APAD+ (Fig. 4B) also displayed substrate inhibition |
741400 |
| 1.1.1.205 | acetylpyridine-NAD+ |
60% as effective as NAD+ |
347946 |
| 1.1.1.205 | beta-NAD+ |
- |
740801 |
| 1.1.1.205 | more |
acetylpyridine adenine dinucleotide |
702243 |
| 1.1.1.205 | more |
involvement of three conserved water molecules (W(L), W(M), and W(C)) in the recognition of catalytic residues (R 322, D 364, and N 303) to cofactor |
704732 |
| 1.1.1.205 | more |
the enzyme shows a clear preference for NAD+ over NADP+, since it loses more than 95% activity when using the latter as co-substrate |
739950 |
| 1.1.1.205 | NAD+ |
- |
347904, 347905, 347906, 347907, 347908, 347909, 347910, 347911, 347912, 347913, 347914, 347915, 347916, 347917, 347918, 347920, 347921, 347923, 347924, 347925, 347926, 347927, 347928, 347929, 347930, 347931, 347932, 347933, 347934, 347935, 347936, 347937, 347938, 347939, 347940, 347941, 347942, 347943, 347944, 347945, 347946, 667219, 667473, 667508, 667626, 667644, 667921, 667935, 667937, 667965, 667980, 668351, 669310, 670881, 701583, 702243, 703193, 703271, 704629, 705494, 705540, 706815, 706817, 724327, 724347, 726097, 736152, 739794, 739950, 740217, 740342, 740417, 740794, 740808, 740809, 741229, 760262, 760699, 760704, 760707, 760826, 760836, 760879, 760962, 760984, 761033, 761406, 761499, 761611, 761676, 761700, 761713, 761804, 761825, 761987, 762347, 762432 |
| 1.1.1.205 | NAD+ |
B-sided stereospecificity: 2-3H of IMP is transferred to pro-S position of carbon atom C-4 of the nicotinamide ring in NAD+ |
347919 |
| 1.1.1.205 | NAD+ |
cofactor-binding site, modelling, overview |
739820 |
