EC Number   |
Cofactor |
Reference |
|---|
   5.1.3.7 | NAD+ |
- |
662221, 716865, 726860, 746866, 747460 |
| 5.1.3.7 | NAD+ |
enzyme-bound, exogenous NAD+ does not appear to be a strong activator of enzyme activity, there is no significant difference in enzyme activity regardless of the presence and absence of NAD+ |
746915 |
| 5.1.3.7 | NAD+ |
highly stimulated by small amounts, Km: 0.13 mM |
2411 |
| 5.1.3.7 | NAD+ |
most potent activator |
2414 |
| 5.1.3.7 | NAD+ |
required |
2416 |
| 5.1.3.7 | NAD+ |
the N-terminal domain harbors the conserved sequence GxxGxxG forming a modified Rossmann-fold involved in binding of the cofactor NAD+ |
747049 |
| 5.1.3.7 | NAD+ |
tight binding to protein during its synthesis |
652005 |
| 5.1.3.7 | NADH |
- |
716865, 726860 |
| 5.1.3.7 | NADH |
stimulates to a lesser gegree than NAD+ |
2414 |
| 5.1.3.7 | NADH |
tight binding to protein during its synthesis |
652005 |
