EC Number |
Cofactor |
Reference |
---|
4.1.1.11 | pyridoxal 5'-phosphate |
- |
727784, 749304 |
4.1.1.11 | pyruvoyl cofactor |
- |
747128 |
4.1.1.11 | pyridoxal 5'-phosphate |
dependent on |
748086 |
4.1.1.11 | pyruvoyl cofactor |
dependent on |
728571, 747497 |
4.1.1.11 | pyruvoyl cofactor |
dependent on, the enzyme contains a covalently-bound pyruvoyl cofactor |
728266 |
4.1.1.11 | pyruvoyl cofactor |
dependent on. Pathway for the formation of the pyruvoyl-dependent cofactor in ADC: the beta-hydroxyl of Ser25 attacks the carbonyl of the previous amino-acid residue (i) to form an oxyoxazolidine intermediate, which decomposes (ii) to form an ester intermediate. E1cB elimination (iii) forms a N-terminal dehydroalanyl residue which is hydrolysed (iv) to form the pyruvoyl cofactor (the alpha'-chain). The ester intermediate can also be hydrolysed to yield the inactive alpha'-chain |
726592 |
4.1.1.11 | more |
requires pyruvate as a covalently bound, catalytically active prosthetic group, pyruvoyl-dependent enzyme, the pyruvoyl group is generated at a specific internal serine residue of the inactive pi-protein with the coincident cleavage of the Gly-Ser bond |
649350 |
4.1.1.11 | pyridoxal 5'-phosphate |
tautomers of the internal aldimine between PLP and enzyme, overview |
727622 |
4.1.1.11 | more |
the ancillary protein PanM (formerly YhhK) is required in vitro and in vivo for cleavage of the L-aspartate-alpha-decarboxylase zymogen |
747435 |
4.1.1.11 | pyridoxal 5'-phosphate |
the enzyme contains pyridoxal 5'-phosphate |
744560 |