EC Number   |
Cofactor |
Reference |
|---|
   1.8.1.8 | coenzyme M |
- |
741927 |
| 1.8.1.8 | FAD |
binding domain structure, residues 210-327 and 450-521, flavoenzyme, the redox-active disulfide in the N-terminal domain, Cys129-Cys132, of the enzyme is in functional communication with the thioredoxin reductase-like disulfide center in the C-terminal portion, Cys345-Cys348, and with FAD |
657677 |
| 1.8.1.8 | FAD |
contains one molecule of flavin adenine dinucleotide per subunit |
680424 |
| 1.8.1.8 | FAD |
tightly but noncovalentyl bound, 1 molecule per subunit, reaction mechanism |
659424 |
| 1.8.1.8 | more |
no cofactor: coenzyme B |
741927 |
| 1.8.1.8 | NAD(P)H |
NADH/SS binding domain structure, residues 328-449, physiological reductant is NADH, NADH is strongly favoured over NADPH |
657677 |
| 1.8.1.8 | NADH |
- |
673557, 687393, 742471 |
| 1.8.1.8 | NADH |
reaction rate with NADPH is approximately twice of that with NADH |
437710 |
| 1.8.1.8 | NADP+ |
tightly but noncovalentyl bound, 1 molecule per subunit, physiological cofactor |
659424 |
| 1.8.1.8 | NADPH |
- |
673557, 687756 |
