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EC Number Cofactor Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.71NADPH the ethanol tolerant phenotype of Clostridium thermocellum is primarily due to a mutated bifunctional acetaldehyde-CoA/alcohol dehydrogenase gene (adhE). The mutant displays a complete loss of NADH-dependent activity with concomitant acquisition of NADPH-dependent activity 739526
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.71NADPH the specificity towards NADP(H) is determined by residues Gly198, Ser199, Arg200 and Tyr218 287275
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