EC Number |
Cofactor |
Reference |
---|
1.17.1.9 | NAD+ |
no activity with NADP+ |
657097 |
1.17.1.9 | NADP+ |
no reaction is catalyzed with wild-type enzyme, activity is detected with mutant enzyme D195S. The ratio of the catalytic efficiencies for NAD+ versus NADP+ for the mutant protein is 40:1 in favor of NAD+ |
288122 |
1.17.1.9 | NAD+ |
preferred cofactor |
725222 |
1.17.1.9 | NAD+ |
specific for NAD+ as electron acceptor |
673381 |
1.17.1.9 | molybdopterin |
the alpha-subunit contains a putative binding motif for the molybdopterin cofactor |
655461 |
1.17.1.9 | NAD+ |
the beta-subunit contains a putative binding motif for NAD+. No activity with NADP+ |
655461 |
1.17.1.9 | NAD+ |
the enzyme prefers to use NAD+ as an electron acceptor more than NADP+ |
763261 |
1.17.1.9 | NADP+ |
the enzyme prefers to use NAD+ as an electron acceptor more than NADP+ |
763261 |
1.17.1.9 | NADP+ |
the wild type enzyme virtually fails to use NADP+ as a cofacor |
686705 |
1.17.1.9 | NAD+ |
wild-type enzyme shows no activity with NADP+, mutant enzyme D196A/Y197R shows higher activity with NADP+ than with NAD+ |
654505 |