EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
2.5.1.15 | -999 |
- |
more |
linear dependency on DHPS concentration when concentration of enzyme versus initial velocity in the coupled enzymatic assay |
691070 |
2.5.1.15 | 0.0024 |
- |
(7,8-dihydropterin-6-yl)methyl diphosphate |
wild-type enzyme, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0024 |
- |
4-Aminobenzoate |
wild-type enzyme, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0029 |
- |
(7,8-dihydropterin-6-yl)methyl diphosphate |
mutant enzyme V585A, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0029 |
- |
4-Aminobenzoate |
mutant enzyme V585A, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0055 |
- |
(7,8-dihydropterin-6-yl)methyl diphosphate |
mutant enzyme A383G, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0055 |
- |
4-Aminobenzoate |
mutant enzyme A383G, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.0057 |
- |
4-Aminobenzoate |
mutant enzyme A437G/K540E, at pH 9.0 and 37°C |
759184 |
2.5.1.15 | 0.006 |
- |
(7,8-dihydropterin-6-yl)methyl diphosphate |
mutant enzyme S382A/A383G/A553G, pH 9.0, 37°C |
758651 |
2.5.1.15 | 0.006 |
- |
4-Aminobenzoate |
mutant enzyme S382A/A383G/A553G, pH 9.0, 37°C |
758651 |