EC Number   |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
|---|
   1.2.1.104 | 0.077 |
- |
pyruvate |
E1 component, pH 7.6, 30°C |
758780 |
| 1.2.1.104 | 3.31 |
- |
thiamine diphosphate |
mutant Y177A, Hill coefficient 1.0, pH 7.0, 30°C |
759457 |
| 1.2.1.104 | 5 |
- |
N-acetyl-GDLLAEIETDK(lipoylated)ATIG-amide |
- |
348994 |
| 1.2.1.104 | 26 |
- |
pyruvate |
pH 7.0, 37°C, mutant S271E of isoform PDH2 |
674778 |
| 1.2.1.104 | 26.3 |
- |
N-terminal lipoyl domain |
- |
348994 |
| 1.2.1.104 | 28.89 |
- |
thiamine diphosphate |
wild-type, Hill coefficient 1.38, pH 7.0, 30°C |
759457 |
| 1.2.1.104 | 29.2 |
- |
pyruvate |
pH 7.0, 37°C, mutant S203A of isoform PDH2 |
674778 |
| 1.2.1.104 | 32.6 |
- |
pyruvate |
pH 7.0, 37°C, mutant S271A of isoform PDH2 |
674778 |
| 1.2.1.104 | 38.1 |
- |
pyruvate |
pH 7.0, 37°C, mutant S203E of isoform PDH2 |
674778 |
| 1.2.1.104 | 66.1 |
- |
pyruvate |
pH 7.0, 37°C, isoform PDH2 |
674778 |
