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EC Number Cloned (Commentary)
Show all pathways known for 2.1.1.254Display the reaction diagram Show all sequences 2.1.1.254-
Show all pathways known for 2.1.1.254Display the reaction diagram Show all sequences 2.1.1.254expression in Escherichia coli
Show all pathways known for 2.1.1.254Display the reaction diagram Show all sequences 2.1.1.254introduction of additional eryK and eryG genes into Saccharopolyspora erythraea shows significant impacts on their transcription levels and enhances the biotransformation process from erythromycin D to erythromycin A with gene dose effects. At the eryK/eryG copy number ratio of 3:2 as well as their resultant transcript ratio of around 2.5:1 to 3.0:1, erythromycin B and erythromycin C are nearly completely eliminated and accordingly converted to erythromycin A
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