  7.5.2.5 | More |
LptB possesses an overall fold resembling that of nucleoside triphosphate-binding (NBD) structures. It contains the canonical L-shaped architecture composed of a RecA-like alpha/beta-ATPase domain and a structurally diverse alpha-helical domain. The RecA-like domain contains the Walker A and Walker B motifs present in many NBD proteins. This domain also furnishes Mg2+- and nucleotide-binding motifs specific to ABC proteins, namely, the Q-loop, which links the more highly conserved alpha/beta-ATPase domain to the alpha-helical domain, and the switch region, which contains the conserved H195 |
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