EC Number |
Subunits |
Reference |
---|
7.4.2.3 | ? |
x * 18000, mass spectrometry, required for import of proteins into mitochondria by presequence translocase-associated motor PAM, stimulates ATPase activity of PAM |
656343 |
7.4.2.3 | ? |
x * 18000, subunit of presequence translocase-associated motor PAM, stimulates ATPase activity of PAM |
657154 |
7.4.2.3 | dimer |
full-legth enzyme in presence of ADP, SDS-PAGE |
698800 |
7.4.2.3 | monomer |
1 * 81000, full-length enzyme in absence of ADP |
698800 |
7.4.2.3 | monomer |
1 * 86000, full-legth enzyme in presence of ADP, SDS-PAGE |
698800 |
7.4.2.3 | More |
DnaK comprises two main domains: a 44-kDa N-terminal nucleotide-binding domain that contains ATPase activity, and a 25-kDa substrate-binding domain that harbors the substrate-binding site. NMR structure determination and analysis of wild-type,full-length DnaK, complexed with the peptide NRLLLTG and with ADP, using NMR residual dipolar coupling and spin labeling methods in aqueous solution based on available crystal structures of the domains, overview |
701016 |
7.4.2.3 | More |
in absence of nucleotides, Hsp70 also forms oligomeric aggregates of high molecular weight |
698800 |
7.4.2.3 | More |
MIM23, MIM17, MIM33 and MIM14 are constituents of the preprotein import machinery of the inner mitochondria membrane. The MIM complex constitutes a proteinaceous channel that accepts preprotein from the mitochonrial outer membrane complex, MOM, facilitates their reversible transmembrane movement, and mediates unidirectional transport by linkage to the ATP-dependent mtHsp70-MIM44 stystem |
210441 |
7.4.2.3 | More |
MIM44 with a MW of 44000 Da is a component of the mitochondrial inner membrane import machinery and interacts with preproteins in an early step of translocation |
210439 |
7.4.2.3 | More |
peripheral membrane protein Tim44 interacts both with the ATPase and peptide-binding domains of enzyme, model for efficient translocation across the mitochondrial inner membrane through regulated interactions |
656858 |