EC Number |
Subunits |
Reference |
---|
5.6.1.1 | ? |
the enzyme consists two subunits, the catalytic p60 subunit and the p80 subunit. ADP-bound p60 is typically monomeric and exchange of ADP to ATP induces hexamerization. The hexameric p60 subunit is active alone, its association with the p80 subunit greatly enhances both the microtubule-binding and microtubule-severing activities of katanin. The interaction between the two katanin subunits is mediated by the p60-MIT domain and the p80 C-terminal domain |
749335 |
5.6.1.1 | ? |
x * 55000, recombinant katanin p60 subunit, SDS-PAGE |
735108 |
5.6.1.1 | ? |
x * 60000, SDS-PAGE |
656593 |
5.6.1.1 | ? |
x * 62000, recombinant protein with His6-tag |
654498 |
5.6.1.1 | ? |
x * 84000, deduced from genen sequence |
655393 |
5.6.1.1 | dimer |
- |
210532, 210533, 210534, 210536, 210537, 210539 |
5.6.1.1 | dimer |
1 * 80000 + 1 * 60000, SDS-PAGE |
210534, 210536, 210537, 210538, 210539 |
5.6.1.1 | dimer |
1 * 81000 + 1 * 60000, SDS-PAGE |
210532, 210533 |
5.6.1.1 | dimer |
Mei-1 + Mei-2, heterodimer analogous to p60/p80 |
210539 |
5.6.1.1 | heterodimer |
- |
673186 |