EC Number   |
Subunits |
Reference |
|---|
   5.1.3.17 | ? |
x * 49905, calculation from nucleotide sequence |
2294 |
| 5.1.3.17 | ? |
x * 52000, liver, SDS-PAGE |
2293 |
| 5.1.3.17 | ? |
x * 68000, about, sequence calculation, x * 75000, recombinant FLAG-tagged enzyme mutant, SDS-PAGE |
747914 |
| 5.1.3.17 | dimer or tetramer |
x * 51914, sequence calculation, x * 52000, recombinant enzyme, SDS-PAGE |
727955 |
| 5.1.3.17 | homodimer |
2 * 60600, recombinant enzyme, SDS-PAGE |
748202 |
| 5.1.3.17 | monomer |
1 * 54000, SDS-PAGE |
2292 |
| 5.1.3.17 | More |
RED-C5-epimerase is present in a dimeric/tetrameric form, in approximately a 2:1 ratio, and appears to be in a dynamic equilibrium |
727955 |
| 5.1.3.17 | More |
the enzyme forms a dimer with two catalytic sites, each at a positively charged cleft in C-terminal alpha-helical domains binding one negatively charged hexasaccharide |
748202 |
| 5.1.3.17 | More |
the human epimerase is a 617-amino acid protein that consists of three domains, cytoplasmic comprising residues Met1-Lys11, transmembrane with Thr12-Trp28, and catalytic domain formed by Asn29-Asn617 |
704649 |
