EC Number   |
Subunits |
Reference |
|---|
   3.4.21.41 | ? |
x * 68000, SDS-PAGE |
753085 |
| 3.4.21.41 | ? |
x * 69500, enzyme fused to maltose binding protein, SDS-PAGE |
753377 |
| 3.4.21.41 | ? |
x * 75900, calculated from amino acid sequence |
753377 |
| 3.4.21.41 | ? |
x * 78000, calculated from amino acid sequence |
753598 |
| 3.4.21.41 | ? |
x * 88000, C1r zymogen, domain structure, overview |
683195 |
| 3.4.21.41 | dimer |
2 * 83000, SDS-PAGE of reduced protein, gel filtration in 6 M guanidinium hydrochloride |
81393 |
| 3.4.21.41 | dimer |
2 * 85000, the C1rbar subunits consist of one polypeptide chain of 56000 Da, A-chain, that is disulfide-linked to a 27000 Da B-chain, SDS-PAGE |
81395 |
| 3.4.21.41 | dimer |
CCP1 is essential to the assembly of the dimer, but formation of a stable dimer is not a prerequisite for self-activation |
652176 |
| 3.4.21.41 | dimer |
deletion of CCP1 domain from CCP1-CCP2-SP fragment results in the loss of the dimeric structure. Dimerization of C1r is not a prerequisite for autoactivation |
652680 |
| 3.4.21.41 | heteropentamer |
C1q, 2 * C1s, 2 * C1r |
717805 |
