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EC Number Subunits Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.24dimer E2 enzymes spontaneeously dimerize in solution, in vitro, in absence of charged ubiquitin 725413
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.24dimer E2 enzymes spontaneously dimerize in solution, in vitro, in absence of charged ubiquitin 725413
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.24monomer 1 * 230000, SDS-PAGE 724254
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.24More the major functional domains of UBE2O include three conserved regions (CR1, CR2, and CR3), a coiled-coil (CC) domain, a UBC domain, and two putative nuclear localization sequences (NLSs). CR1 and CR2 act as substrate-binding domains, although their binding capability is variable, whereas the UBC domain can interact with multiple E3 ligases 759177
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.24More UBE2O shows the Ext-UBC-Ext domain organization 759030
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