5.4.3.8 | More |
the overall structure of AtGSA1 consists of three sequentially arranged domains: the N-terminal domain (Val1-Asp63, mature protein) comprises one alpha-helix and a three-stranded antiparallel beta-sheet, the pyridoxamine 5'-phosphate/pyridoxal 5'-phosphate-binding domain (Tyr64-Gly328), which is also the catalytic domain, contains a central seven-stranded beta-sheet with one antiparallel and six parallel beta-strands, and the C-terminal domain (Thr329-Ile434) is composed of a three-stranded antiparallel beta-sheet with four helices covering the outer surface. Asymmetry of AtGSA1 in the gating-loop conformation, overview |
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