EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   6.3.4.24 | ATP + tyramine + L-glutamate |
the enzyme participates in the biosynthesis of methanofuran, a coenzymes involved in the reduction of carbon dioxide to methane |
Methanocaldococcus fervens |
ADP + phosphate + gamma-glutamyltyramine |
- |
? |
| 6.3.4.24 | ATP + tyramine + L-glutamate |
maximum activity with ATP (100%). Activities with UTP (<0.2%), CTP (<0.08%), and GTP (<0.04%) are much lower. Reactions using tyrosine or phenylalanine instead of tyramine show none of the expected products. Enzymatic reactions including gamma-glutamylglutamate, pyroglutamate, or N-acetyl-glutamate instead of L-glutamate show no expected products. No activity with furyltyramine as substrate. Arg251 is an important residue for both catalysis and glutamate binding |
Methanocaldococcus fervens |
ADP + phosphate + gamma-glutamyltyramine |
- |
? |
| 6.3.4.24 | ATP + tyramine + L-glutamate |
the enzyme participates in the biosynthesis of methanofuran, a coenzymes involved in the reduction of carbon dioxide to methane |
Methanocaldococcus fervens DSM 4213 |
ADP + phosphate + gamma-glutamyltyramine |
- |
? |
| 6.3.4.24 | ATP + tyramine + L-glutamate |
maximum activity with ATP (100%). Activities with UTP (<0.2%), CTP (<0.08%), and GTP (<0.04%) are much lower. Reactions using tyrosine or phenylalanine instead of tyramine show none of the expected products. Enzymatic reactions including gamma-glutamylglutamate, pyroglutamate, or N-acetyl-glutamate instead of L-glutamate show no expected products. No activity with furyltyramine as substrate. Arg251 is an important residue for both catalysis and glutamate binding |
Methanocaldococcus fervens DSM 4213 |
ADP + phosphate + gamma-glutamyltyramine |
- |
? |
