EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.1.8 | 2 glutathione + spermidine + 2 ATP |
trypanothione synthase overall reaction |
Crithidia fasciculata |
N1,N8-bis(glutathionyl)spermidine + 2 ADP + 2 phosphate |
- |
? |
6.3.1.8 | gamma-Glu-Gly-Gly + spermidine + ATP |
at 14% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-Glu-Gly-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-Glu-L-Cys(S-butyl)-Gly + spermidine + ATP |
at 24% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-Glu-L-Cys(S-butyl)-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-Glu-L-Cys(S-ethyl)-Gly + spermidine + ATP |
at 77% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-Glu-L-Cys(S-ethyl)-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-Glu-L-Cys(S-propyl)-Gly + spermidine + ATP |
at 56% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-Glu-L-Cys(S-propyl)-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-Glu-L-Ser-Gly + spermidine + ATP |
at 16% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-Glu-L-Ser-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-L-Glu-L-Ala-Gly + spermidine + ATP |
at 28% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-L-Glu-L-Ala-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-L-Glu-L-alpha-aminobutyryl-Gly + spermidine + ATP |
gamma-L-Glu-L-alpha-aminobutyryl-Gly i.e. ophthalmic acid |
Crithidia fasciculata |
N1-(gamma-L-Glu-L-alpha-aminobutyryl-Gly)-spermidine |
- |
? |
6.3.1.8 | gamma-L-Glu-L-Cys(S-methyl)-Gly + spermidine + ATP |
at 74% of the activity with gamma-L-Glu-L-Cys-Gly |
Crithidia fasciculata |
N1-(gamma-L-Glu-L-Cys(S-methyl)-Gly)-spermidine + ADP + phosphate |
- |
? |
6.3.1.8 | gamma-L-Glu-L-Cys-Gly + spermidine + ATP |
- |
Escherichia coli |
N1-(gamma-L-Glu-L-Cys-Gly)-spermidine + ADP + phosphate |
- |
? |