EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.2.1.45 | ATP + Oregon Green-labeled ubiquitin + [ubiquitin-activating protein E1]-L-cysteine |
enzyme efficiently accepts ubiquitin substrate fluorescently labeled by Oregon Green |
Homo sapiens |
AMP + diphosphate + [ubiquitin-activating protein E1]-S-(Oregon Green-labeled ubiquitinyl)-L-cysteine |
- |
? |
6.2.1.45 | ATP + SUMO2 + [ubiquitin-activating protein UBA5]-L-cysteine |
SUMO2, small ubiquitin-like modifier2, an ubiquitin-like protein |
Homo sapiens |
AMP + diphosphate + [ubiquitin-activating protein UBA5]-S-SUMO2-L-cysteine |
enzyme greatly activates SUMO2 in the nucleus or transfers activated SUMO2 to the nucleus after it conjugated SUMO2 in the cytoplasm |
? |
6.2.1.45 | ATP + ubiquitin + SUMO2 |
UBE1DC1 greatly activates SUMO2 in the nucleus or transfers activated-SUMO2 to nucleus after conjugation of SUMO2 in the cytoplasm |
Homo sapiens |
? |
- |
? |
6.2.1.45 | ATP + ubiquitin + ubiquitin carrier protein E2 |
- |
Homo sapiens |
AMP + diphosphate + ubiquitin-(ubiquitin carrier protein E2) |
- |
? |
6.2.1.45 | ATP + ubiquitin + ubiquitin-fold modifier 1 |
- |
Homo sapiens |
? |
- |
? |
6.2.1.45 | ATP + ubiquitin + Ufm1 |
- |
Homo sapiens |
? |
- |
? |
6.2.1.45 | ATP + ubiquitin + [6His-ubiquitin-activating enzyme E1]W-8His-Strep-HA |
Strep, i.e.WSHPQFEK, HA, i.e. YPYDVPDYAS, under non-reducing conditions, the intermediate complex of the thioester formation is not observed without ATP |
Homo sapiens |
AMP + diphosphate + [6His-ubiquitin-activating enzyme E1]W-8His-Strep-HA-ubiquitinyl-L-cysteine |
- |
? |
6.2.1.45 | ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine |
- |
Drosophila melanogaster |
AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine |
- |
? |
6.2.1.45 | ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine |
- |
Mus musculus |
AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine |
- |
? |
6.2.1.45 | ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine |
- |
Homo sapiens |
AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine |
- |
? |