EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.2.1.40 | ATP + 3-hydroxybutyrate + CoA |
8% of the activity compared to 4-hydroxybutanoate |
Pyrobaculum neutrophilum |
AMP + diphosphate + 3-hydroxybutyryl-CoA |
- |
? |
6.2.1.40 | ATP + 3-hydroxybutyrate + CoA |
8% of the activity compared to 4-hydroxybutanoate |
Pyrobaculum neutrophilum DSM 2338 |
AMP + diphosphate + 3-hydroxybutyryl-CoA |
- |
? |
6.2.1.40 | ATP + 3-hydroxypropionate + CoA |
9% of the activity compared to 4-hydroxybutanoate |
Pyrobaculum neutrophilum |
AMP + diphosphate + 3-hydroxypropionyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
- |
Metallosphaera sedula |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
- |
Pyrobaculum neutrophilum |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
the enzyme is involved in the 3-hydroxypropionate/4-hydroxybutyrate cycle |
Metallosphaera sedula |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
the enzyme has a clear preference for unsubstituted straight chain organic acids with a chain length of four or five carbons. No activity is detected with the six-carbon hexanoic acid |
Metallosphaera sedula |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
tzhe enzyme is also a promiscuous acetate/propionate ligase |
Metallosphaera sedula |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
wild-type enzyme shows no activity, mutant enzyme W424G shows activity |
Metallosphaera sedula |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |
6.2.1.40 | ATP + 4-hydroxybutanoate + CoA |
the enzyme is involved in autotrophic carbon fixation |
Pyrobaculum neutrophilum |
AMP + diphosphate + 4-hydroxybutanoyl-CoA |
- |
? |