EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   5.4.99.27 | more |
for tRNA and Pus7, many known sites and their associated modifiers are identified, including Pus7-dependent sites at position 13 of glutamate tRNA. Pseudouridylation in ncRNAs at sites of inter or intra-molecular interactions |
Saccharomyces cerevisiae |
? |
- |
? |
| 5.4.99.27 | Pyrococcus abyssi tRNAAsp(GUA) uridine13 |
- |
Pyrococcus abyssi |
Pyrococcus abyssi tRNAAsp(GUA) pseudouridine13 |
- |
? |
| 5.4.99.27 | Pyrococcus abyssi tRNATyr(GUA) uridine13 |
some activity at high temperature on tRNAs that contain a U residue at position 13. No activity of is detected at position 35 in the Sulfolobus solfataricus pre-tRNATyr(GUA), even at 80°C |
Saccharolobus solfataricus |
Pyrococcus abyssi tRNATyr(GUA) pseudouridine13 |
- |
? |
| 5.4.99.27 | Pyrococcus abyssi tRNATyr(GUA) uridine13 |
the enzyme modifies tRNAs at position 13 and at other positions as well as intron-less and intron-containing tRNAsTyr(GUA) at position 35 |
Pyrococcus abyssi |
Pyrococcus abyssi tRNATyr(GUA) pseudouridine13 |
- |
? |
| 5.4.99.27 | Pyrococcus abyssi tRNATyr(GUA) uridine35 |
residue 35 reinforces the stability of the anticodon stemloop by interaction with residue U33 (13). This structural stabilization may increase the aminoacylation efficiency of tRNATyr(GUA) by its cognate aminoacyl-tRNA synthetase |
Pyrococcus abyssi |
Pyrococcus abyssi tRNATyr(GUA) pseudouridine35 |
- |
? |
| 5.4.99.27 | Pyrococcus abyssi tRNATyr(GUA) uridine35 |
the enzyme modifies tRNAs at position 13 and at other positions as well as intron-less and intron-containing tRNAsTyr(GUA) at position 35 |
Pyrococcus abyssi |
Pyrococcus abyssi tRNATyr(GUA) pseudouridine35 |
- |
? |
| 5.4.99.27 | tRNA uridine13 |
- |
Escherichia coli |
tRNA pseudouridine13 |
- |
? |
| 5.4.99.27 | tRNA uridine13 |
- |
Saccharomyces cerevisiae |
tRNA pseudouridine13 |
- |
? |
| 5.4.99.27 | tRNA uridine13 |
- |
Homo sapiens |
tRNA pseudouridine13 |
- |
? |
| 5.4.99.27 | tRNA uridine13 |
Pus7p is a multisite-multisubstrate RNA:PSI-synthase. Recombinant Pus7p has tRNAAsp:pseudouridine13- and pre-RNATyr:pseudouridine35-synthase activities |
Saccharomyces cerevisiae |
tRNA pseudouridine13 |
- |
? |
