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Results 1 - 10 of 32 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12Escherichia coli tRNAPhe uridine39 - Escherichia coli Escherichia coli tRNAPhe pseudouridine39 - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12human tRNALeu uridine 38 uridine39 - Mus musculus human tRNALeu pseudouridine 38 pseudouridine39 psuedouridine formation in position 39 is clearly preferred over position 38 ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12human tRNALys3 - Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12human tRNASer uridine39 - Mus musculus human tRNASer pseudouridine39 - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12more presence of a G36 residue modulates modification at position 38. In addition to local sequence effects, steady-state kinetic analyses suggest the existence of other recognition elements distinct from the immediate vicinity of modification Escherichia coli ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12Salmonella typhimurium HisT- tRNALeu tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3'-side of the anticodon region of approximately half of the cellular tRNAs Bos taurus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12Salmonella typhimurium HisT- tRNAPhe2 uridine39 tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3’ side of the anticodon region of approximately half of the cellular tRNAs Bos taurus Salmonella typhimurium HisT- tRNAPhe2 pseudouridine39 specific modification of uridine39 ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12Salmonelly typhimurium HisT- tRNATyr tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3'-side of the anticodon region of approximately half of the cellular tRNAs Bos taurus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12tRNA uridine38 - Saccharomyces cerevisiae tRNA pseudouridine38 - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.12tRNA uridine38 tRNALeu3 contains uridine at position 38. Wild-typeTruA pseudouridylates uridines at all three positions (38, 39 and 40) with efficiencies (kcat/KM) differing by less than 10fold, while R58A is inactive toward all three uridines. When flexibility of the anticodon stem loop is increased by mutating the two G:C base pairs in the stem of the anticodon stem loop of tRNALeu3 into A:U pairs, the kcat/KM increased 2fold. When flexibility is decreased by base-pairing the target U38 of tRNALeu3 with A32 instead of with U32, the kcat/KM decreases 10fold Escherichia coli tRNA pseudouridine38 - ?
Results 1 - 10 of 32 > >>