EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate |
- |
Homo sapiens |
(5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate |
- |
? |
| 5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate |
- |
Homo sapiens |
(5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate |
i.e. TXA2 |
? |
| 5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate |
- |
Aloe vera |
(5Z,13E)-(15S)-9alpha,11alpha-epoxy-15-hydroxythromboxa-5,13-dienoate |
i.e. TXA2 |
? |
| 5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate |
- |
Homo sapiens |
12-L-hydroxy-5,8,10-heptadecaotrienoic acid + malondialdehyde |
ratio of TXA2/heptadecatrienoic acid/malondialdehyde, 1/1/1 |
? |
| 5.3.99.5 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate |
- |
Aloe vera |
(5Z,13E)-(15S)-9a,11a-epoxy-15-hydroxythromboxa-5,13-dienoate |
i.e. TXA2 |
? |
| 5.3.99.5 | 15(S)-Hydroxy-11alpha,9alpha-epoxymethano-5(Z),13(E)-prostadienoic acid |
in presence of iodosylbenzene |
Homo sapiens |
? |
3 different hydroxylated derivatives of 15(S)-hydroxy-11alpha,9alpha-epoxymethano-5(Z),13(E)-prostadienoic acid |
? |
| 5.3.99.5 | 15-hydroperoxyeicosatetraenoic acid |
- |
Homo sapiens |
13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic acid + 15-ketoeicosatetraenoic acid + 13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic acid + 15-ketoeicosatetraenoic acid |
13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic acid and 15-ketoeicosatetraenoic acid result from homolytic cleavage of the O-O bond, whereas 13-hydroxy-14,15-epoxy-5,8,11-eicosatrienoic acid + 15-ketoeicosatetraenoic acid results from heterolytic cleavage. About 60% of substrate is cleaved homolytically, and maximal velocity of homolytic cleavage is about 1.4fold faster than heterolytic cleavage |
? |
| 5.3.99.5 | 15-hydroxy-9alpha,11alpha-peroxiprosta-5,13-dienoic acid |
- |
Sus scrofa |
? |
- |
? |
| 5.3.99.5 | 15-Ketoprostaglandin H2 |
- |
Homo sapiens |
? |
- |
? |
| 5.3.99.5 | 2 prostaglandin G2 |
i.e. PGG2 |
Homo sapiens |
15-hydroperoxythromboxane A2 + 12-hydroperoxy-5,8,10-heptadecatrienoic acid |
the reaction products are transformed to thromboxane B2 and 12-hydroxy-5,8,10-heptadecatrienoic acid by SnCl2 reduction and to 12-keto-5,8,10-heptadecatrienoic acid and 15-ketothromboxane B2 by lead tetraacetate dehydration |
? |
