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Results 1 - 3 of 3
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 5.1.2.7D-fructuronate - Thermotoga maritima D-tagaturonate - r
Display the reaction diagram Show all sequences 5.1.2.7D-tagaturonate - Thermotoga maritima D-fructuronate - r
Display the reaction diagram Show all sequences 5.1.2.7more residue Asp161 likely interacts with the C3 hydroxyl group of D-TagA and deprotonates it. A divalent cation (likely Zn2+) chelated by His162 and possibly interacts with the C5 keto and C4 hydroxyl groups of D-TagA, thereby contributing to the cleavage of the adjacent C3-C4 bond. A carboxyl group of Glu266 then may promote the rotation and reprotonation of the C3 aldehyde group in the intermediate and the restoration of the broken C3-C4 bond to form D-FruA Thermotoga maritima ? - ?
Results 1 - 3 of 3