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Results 1 - 10 of 10
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate - Streptomyces sp. (+)-cubenene + diphosphate reaction proceeds via 1,3-hydride shift. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. Cyclization of [ 13,13,13-2H3]farnesy1 diphosphate with crude epicubenol synthase gives [ 13,13,13-2H3]epicubenol ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrate Streptomyces sp. (+)-cubenene + diphosphate - ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrate Streptomyces sp. (+)-cubenene + diphosphate reaction proceeds via 1,2- and 1,3-hydride shifts. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. The initial isomerization of farnesyl diphosphate to (3R)-nerolidyl diphosphate takes place with suprafacial stereochemistry. Ionization of (3R)-nerolidyl diphosphate and attack by the 10-11 double bond on the re face of the cisoid allylic cation-diphosphate anion pair generates the cis-germacradienyl cation. A second electrophilic cyclization gives the cadinanyl cation, which upon a 1.2-hydride shift and syn capture of water generates epicubenol ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrae Heteroscyphus planus (+)-cubenene + diphosphate (+)-cubenene synthase and (+)-epicubenol synthase are dual functions of the same enzyme ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrae Heteroscyphus planus (+)-cubenene + diphosphate reaction proceeds via 1,2- and 1,3-hydride shifts ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate - Streptomyces sp. LL-B7 (+)-cubenene + diphosphate reaction proceeds via 1,3-hydride shift. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. Cyclization of [ 13,13,13-2H3]farnesy1 diphosphate with crude epicubenol synthase gives [ 13,13,13-2H3]epicubenol ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrate Streptomyces sp. LL-B7 (+)-cubenene + diphosphate - ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate specific substrate Streptomyces sp. LL-B7 (+)-cubenene + diphosphate reaction proceeds via 1,2- and 1,3-hydride shifts. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. The initial isomerization of farnesyl diphosphate to (3R)-nerolidyl diphosphate takes place with suprafacial stereochemistry. Ionization of (3R)-nerolidyl diphosphate and attack by the 10-11 double bond on the re face of the cisoid allylic cation-diphosphate anion pair generates the cis-germacradienyl cation. A second electrophilic cyclization gives the cadinanyl cation, which upon a 1.2-hydride shift and syn capture of water generates epicubenol ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate + H2O specific substrate Streptomyces sp. (+)-epicubenol + diphosphate reaction proceeds via 1,2- and 1,3-hydride shifts. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. The initial isomerization of farnesyl diphosphate to (3R)-nerolidyl diphosphate takes place with suprafacial stereochemistry. Ionization of (3R)-nerolidyl diphosphate and attack by the 10-11 double bond on the re face of the cisoid allylic cation-diphosphate anion pair generates the cis-germacradienyl cation. A second electrophilic cyclization gives the cadinanyl cation, which upon a 1.2-hydride shift and syn capture of water generates epicubenol ?
Display the reaction diagram Show all sequences 4.2.3.63(2E,6E)-farnesyl diphosphate + H2O specific substrate Streptomyces sp. LL-B7 (+)-epicubenol + diphosphate reaction proceeds via 1,2- and 1,3-hydride shifts. (3R)-nerolidyl diphosphate is an intermediate in the cyclization. The initial isomerization of farnesyl diphosphate to (3R)-nerolidyl diphosphate takes place with suprafacial stereochemistry. Ionization of (3R)-nerolidyl diphosphate and attack by the 10-11 double bond on the re face of the cisoid allylic cation-diphosphate anion pair generates the cis-germacradienyl cation. A second electrophilic cyclization gives the cadinanyl cation, which upon a 1.2-hydride shift and syn capture of water generates epicubenol ?
Results 1 - 10 of 10