EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
- |
Pogostemon cablin |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
- |
Streptomyces avermitilis |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
66% |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
- |
Streptomyces coelicolor |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
trans-1,10-dimethyl-trans-9-decalol |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
enzyme is essential for geosmin biosynthesis |
Streptomyces coelicolor |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
enzyme is involved in geosmin biosynthesis |
Streptomyces coelicolor |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
cyclization reaction, mechanism of full length enzyme and N-terminal catalytic domain |
Streptomyces coelicolor |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
reaction is catalyzed by one of two sesquiterpene domains of the enzyme |
Streptomyces coelicolor |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
Mg-dependent conversion |
Streptomyces peucetius |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
enzyme is involved in geosmin biosynthesis |
Streptomyces coelicolor A3(2) |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |
4.2.3.22 | (2E,6E)-farnesyl diphosphate + H2O |
cyclization reaction, mechanism of full length enzyme and N-terminal catalytic domain |
Streptomyces coelicolor A3(2) |
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate |
- |
? |