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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
4.2.3.131
(+)-copalyl diphosphate
-
Salvia miltiorrhiza
miltiradiene + diphosphate
-
?
4.2.3.131
(+)-copalyl diphosphate
-
Salvia rosmarinus
miltiradiene + diphosphate
-
?
4.2.3.131
(+)-copalyl diphosphate
-
Salvia fruticosa
miltiradiene + diphosphate
-
?
4.2.3.131
(+)-copalyl diphosphate
-
Isodon rubescens
miltiradiene + diphosphate
-
?
4.2.3.131
(+)-copalyl diphosphate
-
Tripterygium wilfordii
miltiradiene + diphosphate
-
?
4.2.3.131
(+)-copalyl diphosphate
-
Salvia miltiorrhiza
miltiradiene + diphosphate
the enzyme is quite specific in its production of miltiradiene with more than 95% of the total product output
?
4.2.3.131
(+)-copalyl diphosphate
-
Salvia rosmarinus
miltiradiene + diphosphate
products are abietatriene and miltiradiene, ratio of miltiradiene to abietatriene is 100:30. Miltiradiene spontaneously reacts to abietatriene
?
4.2.3.131
8-hydroxy-(+)-copalyl diphosphate
-
Salvia rosmarinus
manoyl oxide + diphosphate
-
?
4.2.3.131
geranylgeranyl diphosphate
-
Salvia rosmarinus
(+)-copalyl diphosphate
-
r
4.2.3.131
more
MDS is a bifunctional miltiradiene synthase catalyzing the cyclization reaction of geranylgeranyl diphosphate via (+)-copalyl diphosphate to afford miltiradiene as a final product
Salvia miltiorrhiza
?
-
?
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