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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.121'-3H-dihydroneopterin triphosphate tritium released is not incorporated in the product Bos taurus 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.122'-3H-dihydroneopterin triphosphate tritium released is not incorporated in the product Bos taurus 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-monophosphate)-7,8-dihydropterin the binding constant is 225fold increased with respect to the natural substrate Rattus norvegicus 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + monophosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin - Escherichia coli 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin - Homo sapiens 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin - Rattus norvegicus 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin - Salmo salar 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin - Plasmodium falciparum 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin one of the enzymes involved in tetrahydrobiopterin biosynthesis Salmo salar 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
Show all pathways known for 4.2.3.12Display the word mapDisplay the reaction diagram Show all sequences 4.2.3.126-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin 23 bp exon 3 skipping in transcription rather than post-transcriptional mechanisms is a major cause of the low PTPS protein expression in human macrophages and related cell types. The exon lacking leads to a premature stop codon encoding for a shorter protein instead of the full-length functional enzyme Homo sapiens 6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin + triphosphate - ?
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