EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.1.2.51 | 2-dehydro-3-deoxy-D-galactonate |
- |
Picrophilus torridus |
pyruvate + D-glyceraldehyde |
- |
? |
4.1.2.51 | 2-dehydro-3-deoxy-D-galactonate |
the enzyme shows substrate promiscuity, as measured in the direction of aldol synthesis. The enzyme catalyzes the formation of both 2-dehydro-3-deoxy-D-gluconate and its C-4 epimer 2-keto-3-deoxygalactonate from D- or L-glyceraldehyde and pyruvate at a similar ratio, indicating lack of stereospecific control in formation and cleavage of 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate |
Picrophilus torridus |
pyruvate + D-glyceraldehyde |
- |
r |
4.1.2.51 | 2-dehydro-3-deoxy-D-gluconate |
the enzyme from the archaeon Picrophilus torridus is involved in D-glucose and D-galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway |
Picrophilus torridus |
pyruvate + D-glyceraldehyde |
- |
? |
4.1.2.51 | 2-dehydro-3-deoxy-D-gluconate |
highly specific for 2-dehydro-3-deoxy-D-gluconate with up to 2000fold-higher catalytic efficiency compared to 2-dehydro-3-deoxy-6-phosphogluconate |
Picrophilus torridus |
pyruvate + D-glyceraldehyde |
- |
? |
4.1.2.51 | 2-dehydro-3-deoxy-D-gluconate 6-phosphate |
highly specific for 2-dehydro-3-deoxy-D-gluconate with up to 2000fold-higher catalytic efficiency compared to 2-dehydro-3-deoxy-6-phosphogluconate |
Picrophilus torridus |
pyruvate + D-glyceraldehyde 3-phosphate |
- |
? |